High precision, High quality,
Ultra-precision machining technology

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MEDICAL・BIOTECHNOLOGY

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Microwell chip for single cell analysis

Technology to observe live cells one by one and analyze (single cell analysis)

Development of advanced medical technology such as new drug discovery development, regenerative medical technology, IPS cell research and development

A technology that dramatically improves the efficiency of isolated single cell analysis for research on regenerative medicine and drug discovery

Significantly increase the number of wells per unit area

Cells have been traditionally treated as colonies. For that reason, colonies contained several other cells besides the target cells, and these cells caused noise and increased the variability of the experiment. In order to minimize variation, it is necessary to sort and analyze the cells into a single, and in order to analyze efficiently, it is indispensable to perform a lot of cell analysis at the same time. It was realized that, This is a narrow pitch microwell chip.

Characteristic

1. Ultra precision well chip

  • Well size: 30 microns x 15 microns x depth 30 microns
  • Material: Zeonor (manufactured by Zeon Corporation)
  • Number of wells: 40,000 well / TIP

By using precision micromachined metal mold, injection molding is carried out, realizing a highly accurate well chip!
Especially by improving the accuracy of the bottom part, we can improve the capture efficiency. It also realizes super-resolution live cell imaging.

Bio-microwell chip

40,000Well

40,000Well

Hexagonal array

Hexagonal array

Well arrangement ( × 1000 )

2. Ultra precision narrow pitch

  • Flat pitch between wells: 10 microns or less
  • Size that contains only one cell

Cells are less likely to remain on the top of the plate, making analysis possible in a short time.
By increasing the number of wells per unit area, it contributes to improvement of analysis efficiency.

Well Detailed View:Realized less then 10μm!

Single cell

single cell

3. Ability to analyze large quantities of cells at once

By combining microwell chips, it is possible to analyze a large amount of cells at one time

Micro well chip for new drug discovery single cell analysis (resin product)

Precision micro machined aluminum alloy mold is used, precision injection molding is performed, realizing a highly accurate well chip!
Especially by improving the accuracy of the bottom part, we can improve the capture efficiency. It can also support super-resolution live cell imaging.

40,000 Well
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